Article
Mutation spectrum and differential gene expression in cystic and solid vestibular schwannoma.
Genetics in medicine : official journal of the American College of Medical Genetics - 1 Mar 2014
Zhang Zhihua, Wang Zhaoyan, Sun Lianhua, Li Xiaohua, Huang Qi, Yang Tao, Wu Hao
Abstract excerpt
PURPOSE: We sought to characterize the mutation spectrum of NF2 and the differential gene expression in cystic and solid vestibular schwannomas. METHODS: We collected tumor tissue and blood samples of 31 cystic vestibular schwannomas and 114 solid vestibular schwannomas. Mutation screening of NF2 was performed in both tumor and blood DNA samples of all patients. cDNA microarray was used to analyze the...
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