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Article

Analysis of the clonal growth and differentiation dynamics of primitive barcoded human cord blood cells in NSG mice

12 Sept 2013

Abstract excerpt

Human cord blood (CB) offers an attractive source of cells for clinical transplants because of its rich content of cells with sustained repopulating ability in spite of an apparent deficiency of cells with rapid reconstituting ability. Nevertheless, the clonal dynamics of nonlimiting CB transplants remain poorly understood. To begin to address this question, we exposed CD34+ CB cells to a library of barcoded...

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PMID: 24030380
DOI: 10.1182/blood-2013-06-508432

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