Article
Prevention of graft rejection in allogeneic bone marrow transplantation. II. Preclinical studies with three radiation protocols.
Transplantation - 1 Sept 1990
Malilay G P, Sevenich E A, Filipovich A H
Abstract excerpt
Three radiotherapeutic regimens were compared in vitro to determine their immunosuppressive potential against non-MHC-restricted cytotoxic cells. Assays of natural killer and lymphokine-activated killer function, and cytotoxicity against allogeneic cells were used to quantitate the cytotoxic pote...
Topics
- Bone Marrow Transplantation
- Cesium Radioisotopes
- Cytotoxicity, Immunologic
- Dose-Response Relationship, Radiation
- Graft Rejection
- Humans
- In Vitro Techniques
- Interleukin-2
- Killer Cells, Lymphokine-Activated
- Killer Cells, Natural
- Leukocytes, Mononuclear
- Lymphocyte Depletion
- Phenotype
- Postoperative Complications
- T-Lymphocytes