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Article

A model for cofactor use during HIV-1 reverse transcription and nuclear entry

14 Jan 2014

Abstract excerpt

Lentiviruses have evolved to infect and replicate in a variety of cell types in vivo whilst avoiding the powerful inhibitory activities of restriction factors or cell autonomous innate immune responses. In this review we offer our opinions on how HIV-1 uses a series of host proteins as cofactors for infection. We present a model that may explain how the capsid protein has a fundamental role in the early part of...

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Identifiers

PMID: 24525292
DOI: 10.1016/j.coviro.2013.11.003

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