Genetic profile and determinants of homocysteine levels in Kazakhstan patients with breast cancer.

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Genetic profile and determinants of homocysteine levels in Kazakhstan patients with breast cancer.

Anticancer research - 1 Sept 2013

Akilzhanova Ainur, Nurkina Zhannur, Momynaliev Kuvat, Ramanculov Erlan, Zhumadilov Zhaxibai, Zhumadilov Zhaxybai, Rakhypbekov Tolebay, Hayashida Naomi, Nakashima Masahiro, Takamura Noboru

Abstract excerpt

AIM: To analyze associations between homocysteine level, MTHFR and FTO rs1477196 polymorphisms and folate status in patients with breast cancer (BC) in order to clarify determinants of hyperhomocysteinemia. PATIENTS AND METHODS: The study included 315 BC cases and 604 controls. RESULTS: The MTHFRC677T genotype was associated with an increased incidence of BC [Odds ratio (OR)=1.71; 95% Confidential interval...

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PMID: 24023349

Genes

MTHFR
FTO

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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