Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A problem of persistence: still more questions than answers?

Nature reviews. Microbiology - 1 Aug 2013

Balaban Nathalie Q, Gerdes Kenn, Lewis Kim, McKinney John D

Abstract excerpt

The current antibiotic resistance crisis has led to increased pressure to prioritize strategies to tackle the issue, with a strong focus being placed on the development of novel antimicrobials. However, one major obstacle that is often overlooked is persister cells, which are refractory to antibiotic treatment. Tackling persistence is a challenge because these cell types are extremely difficult to study and,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-Bacterial Agents
Share to Bacteria
Share to Bacterial Infections

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Resistance, Bacterial

Share to Microbial Viability

Share to Reactive Oxygen Species

Share to Species Specificity

Share to Stress, Physiological

Source

Identifiers

PMID: 24020075
DOI: 10.1038/nrmicro3076

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A problem of persistence: still more questions than answers?PMID 24020075Read ↗

New-found fundamentals of bacterial persistence.Semantic proximity Read ↗

Antibiotic-tolerant persisters are pervasive among clinical <i>Streptococcus pneumoniae</i> isolates and show strong condition-dependenceSemantic proximity Read ↗

Fighting bacterial persistence: Current and emerging anti-persister strategies and therapeutics.Semantic proximity Read ↗

Antibiotic Tolerance Indicative of Persistence Is Pervasive among Clinical Streptococcus pneumoniae Isolates and Shows Strong Condition Dependence.Semantic proximity Read ↗

Isolation and characterization of persisters of the pathogenic microorganism <i>Staphylococcus aureus</i>Semantic proximity Read ↗

Bacterial persistence as a phenotypic switch.Semantic proximity Read ↗

Bacterial persistence from a system-level perspective.Semantic proximity Read ↗

The importance of being persistent: heterogeneity of bacterial populations under antibiotic stress.Semantic proximity Read ↗

Relationship between the Viable but Nonculturable State and Antibiotic Persister Cells.Semantic proximity Read ↗

Phenotypic and genetic heterogeneity within biofilms with particular emphasis on persistence and antimicrobial tolerance.Semantic proximity Read ↗

Isolation and characterization of persisters of the pathogenic microorganism Staphylococcus aureusSemantic proximity Read ↗

Molecular physiological characterization of the dynamics of persister formation in <i>Staphylococcus aureus</i>Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.