Article
Phenotypic and genetic heterogeneity within biofilms with particular emphasis on persistence and antimicrobial tolerance.
Future microbiology - 1 Sept 2017
Sadiq Faizan A, Flint Steve, Li YanJun, Ou Kai, Yuan Lei, He Guo Qing
Abstract excerpt
Phenotypic changes or phase variation within biofilms is an important feature of bacterial dormant life. Enhanced resistance to antimicrobials is one of the distinct features displayed by a fraction of cells within biofilms. It is believed that persisters are mainly responsible for this phenotypic heterogeneity. However, there is still an unresolved debate on the formation of persisters. In this short review, we...
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