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Article

Promoter region architecture and transcriptional regulation of the genes for the MHC class I-related chain A and B ligands of NKG2D.

Journal of immunology (Baltimore, Md. : 1950) - 15 Jan 2007

Venkataraman Gopalakrishnan M, Suciu Dominic, Groh Veronika, Boss Jeremy M, Spies Thomas

Abstract excerpt

Ligands of the NKG2D receptor, which activates NK cells and costimulates effector T cells, are inducibly expressed under harmful conditions, such as malignancies and microbial infections. Moreover, aberrant expression in autoimmune disease lesions may contribute to disease progression. Among these ligands are the closely related human MHC class I-related chains (MIC) A and B, which appear to be regulated by...

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Identifiers

PMID: 17202358
DOI: 10.4049/jimmunol.178.2.961

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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