Article
The JIL-1 kinase interacts with lamin Dm0 and regulates nuclear lamina morphology of Drosophila nurse cells.
Journal of cell science - 1 Nov 2005
Bao Xiaomin, Zhang Weiguo, Krencik Robert, Deng Huai, Wang Yanming, Girton Jack, Johansen Jørgen, Johansen Kristen M
Abstract excerpt
We have used a yeast two-hybrid screen to identify lamin Dm0 as an interaction partner for the nuclear JIL-1 kinase. This molecular interaction was confirmed by GST-fusion protein pull-down assays and by co-immunoprecipitation experiments. Using deletion construct analysis we show that a predicted globular domain of the basic region of the COOH-terminal domain of JIL-1 was sufficient for mediating the molecular...
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