Article
Selective nucleic acid removal via exclusion (SNARE): capturing mRNA and DNA from a single sample.
Analytical chemistry - 15 Oct 2013
Strotman Lindsay, O'Connell Rachel, Casavant Benjamin P, Berry Scott M, Sperger Jamie M, Lang Joshua M, Beebe David J
Abstract excerpt
The path from gene (DNA) to gene product (RNA or protein) is the foundation of genotype giving rise to phenotype. Comparison of genomic analyses (DNA) with paired transcriptomic studies (mRNA) is critical to evaluating the pathogenic processes that give rise to human disease. The ability to analyze both DNA and mRNA from the same sample is not only important for biologic interrogation but also to minimize...
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