Article
Deletions affecting hemolytic and toxin activities of Bordetella pertussis adenylate cyclase.
Infection and immunity - 1 Oct 1990
Bellalou J, Sakamoto H, Ladant D, Geoffroy C, Ullmann A
Abstract excerpt
The Bordetella pertussis cyaA gene encodes a virulence factor which is a bifunctional protein exhibiting calmodulin-sensitive adenylate cyclase and hemolytic activities (P. Glaser, H. Sakamoto, J. Bellahov, A. Ullmann, and A. Danchin, EMBO J. 7:3997-4004, 1988). We characterized the hemolytic and toxin activities of the 200-kilodalton (kDa) bifunctional (CyaA) protein and showed that, whether cell associated or...
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