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Article

Deletions affecting hemolytic and toxin activities of Bordetella pertussis adenylate cyclase.

Infection and immunity - 1 Oct 1990

Bellalou J, Sakamoto H, Ladant D, Geoffroy C, Ullmann A

Abstract excerpt

The Bordetella pertussis cyaA gene encodes a virulence factor which is a bifunctional protein exhibiting calmodulin-sensitive adenylate cyclase and hemolytic activities (P. Glaser, H. Sakamoto, J. Bellahov, A. Ullmann, and A. Danchin, EMBO J. 7:3997-4004, 1988). We characterized the hemolytic and toxin activities of the 200-kilodalton (kDa) bifunctional (CyaA) protein and showed that, whether cell associated or...

Topics

Adenylyl Cyclases
Bacterial Toxins
Bordetella pertussis
Chromosome Deletion
Erythrocytes
Hemolysin Proteins
Immunoblotting
Mutation

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 2401563
DOI: 10.1128/iai.58.10.3242-3247.1990
PMCID: PMC313645

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2401563-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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