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Article

Epitope mapping of monoclonal antibodies against Bordetella pertussis adenylate cyclase toxin.

Infection and immunity - 1 May 1999

Lee S J, Gray M C, Guo L, Sebo P, Hewlett E L

Abstract excerpt

Adenylate cyclase (AC) toxin from Bordetella pertussis is a 177-kDa repeats-in-toxin (RTX) family protein that consists of four principal domains; the catalytic domain, the hydrophobic domain, the glycine/aspartate-rich repeat domain, and the secretion signal domain. Epitope mapping of 12 monoclonal antibodies (MAbs) directed against AC toxin was conducted to identify regions important for the functional...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 10225859
DOI: 10.1128/IAI.67.5.2090-2095.1999
PMCID: PMC115942

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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