Article
Effects of polymorphisms in translesion DNA synthesis genes on lung cancer risk and prognosis in Chinese men.
Cancer epidemiology - 1 Dec 2013
Xu Hong-Li, Gao Xiao-Rong, Zhang Wei, Cheng Jia-Rong, Tan Yu-Ting, Zheng Wei, Shu Xiao-Ou, Xiang Yong-Bing
Abstract excerpt
PURPOSE: Translesion DNA synthesis (TLS) plays an important role in promoting replication through DNA lesions. Genetic polymorphisms in TLS genes may have potential roles in lung cancer development in humans. METHODS: We evaluated the association between genetic variants in six TLS genes and the risk and survival of lung cancer in a case-control study in China. Included in the study are 224 lung cancer patients...
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