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Article

K(ATP)-channel-dependent regulation of catecholaminergic neurons controls BAT sympathetic nerve activity and energy homeostasis.

Cell metabolism - 3 Sept 2013

Tovar Sulay, Paeger Lars, Hess Simon, Morgan Donald A, Hausen A Christine, Brönneke Hella S, Hampel Brigitte, Ackermann P Justus, Evers Nadine, Büning Hildegard, Wunderlich F Thomas, Rahmouni Kamal, Kloppenburg Peter, Brüning Jens C

Abstract excerpt

Brown adipose tissue (BAT) is a critical regulator of glucose, lipid, and energy homeostasis, and its activity is tightly controlled by the sympathetic nervous system. However, the mechanisms underlying CNS-dependent control of BAT sympathetic nerve activity (SNA) are only partly understood. Here, we demonstrate that catecholaminergic neurons in the locus coeruleus (LC) adapt their firing frequency to...

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Source

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Identifiers

PMID: 24011078
DOI: 10.1016/j.cmet.2013.08.006
PMCID: PMC5684875

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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