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Article

Intraclonal variations among Streptococcus pneumoniae isolates influence the likelihood of invasive disease in children.

The Journal of infectious diseases - 1 Feb 2014

Browall Sarah, Norman Martin, Tångrot Jeanette, Galanis Ilias, Sjöström Karin, Dagerhamn Jessica, Hellberg Christel, Pathak Anuj, Spadafina Tiziana, Sandgren Andreas, Bättig Patrick, Franzén Oscar, Andersson Björn, Örtqvist Åke, Normark Staffan, Henriques-Normark Birgitta

Abstract excerpt

BACKGROUND: Pneumococcal serotypes are represented by a varying number of clonal lineages with different genetic contents, potentially affecting invasiveness. However, genetic variation within the same genetic lineage may be larger than anticipated. METHODS: A total of 715 invasive and carriage isolates from children in the same region and during the same period were compared using pulsed-field gel...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24009156
DOI: 10.1093/infdis/jit481
PMCID: PMC4014860

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