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Article

Identification of a Candidate Streptococcus pneumoniae core genome and regions of diversity correlated with invasive pneumococcal disease.

Infection and immunity - 1 Aug 2006

Obert Caroline, Sublett Jack, Kaushal Deepak, Hinojosa Ernesto, Barton Theresa, Tuomanen Elaine I, Orihuela Carlos J

Abstract excerpt

Streptococcus pneumoniae is a leading cause of community-acquired pneumonia and gram-positive sepsis. While multiple virulence determinants have been identified, the combination of features that determines the propensity of an isolate to cause invasive pneumococcal disease (IPD) remains unknown. In this study, we determined the genetic composition of 42 invasive and 30 noninvasive clinical isolates of serotypes...

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Identifiers

PMID: 16861665
DOI: 10.1128/IAI.00316-06
PMCID: PMC1539573

Genes

CGA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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