Article
Analysis of invasiveness of pneumococcal serotypes and clones circulating in Portugal before widespread use of conjugate vaccines reveals heterogeneous behavior of clones expressing the same serotype.
Journal of clinical microbiology - 1 Apr 2011
Sá-Leão Raquel, Pinto Francisco, Aguiar Sandra, Nunes Sónia, Carriço João A, Frazão Nelson, Gonçalves-Sousa Natacha, Melo-Cristino José, de Lencastre Hermínia, Ramirez Mário
Abstract excerpt
To estimate the invasive disease potential of serotypes and clones circulating in Portugal before extensive use of the seven-valent pneumococcal conjugate vaccine, we analyzed 475 invasive isolates recovered from children and adults and 769 carriage isolates recovered from children between 2001 and 2003. Isolates were serotyped and genotyped by pulsed-field gel electrophoresis, and a selection of isolates were...
Topics
- Adolescent
- Adult
- Bacterial Typing Techniques
- Carrier State
- Child
- Child, Preschool
- Electrophoresis, Gel, Pulsed-Field
- Genotype
- Heptavalent Pneumococcal Conjugate Vaccine