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Article

Identification of hematopoietic progenitors of macrophages and dendritic Langerhans cells (DL-CFU) in human bone marrow and peripheral blood.

Blood - 15 Sept 1990

Reid C D, Fryer P R, Clifford C, Kirk A, Tikerpae J, Knight S C

Abstract excerpt

Colonies of cells with distinctive dendritic appearance were observed in methylcellulose cultures of human bone marrow and peripheral blood mononuclear cells (PBMC). Such cells appeared alone in colonies of less than 50 cells, together with macrophages in mixed colonies and also within clusters of T lymphocytes at high culture cell numbers. The morphologic resemblance to lymphoid dendritic cells was confirmed by...

Topics

Antibodies, Monoclonal
Autoradiography
Blood Cells
Bone Marrow
Bone Marrow Cells
Dendritic Cells
Hematopoiesis
Hematopoietic Stem Cells
Histocytochemistry
Humans
Langerhans Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Leukocytes

Macrophages

Microscopy, Electron

Phenotype

Source

Identifiers

PMID: 2400808

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2400808-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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