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Article

Characterization of primitive hematopoietic cells from patients with dyskeratosis congenita.

Blood - 1 May 2008

Goldman Frederick D, Aubert Geraldine, Klingelhutz Al J, Hills Mark, Cooper Sarah R, Hamilton Wendy S, Schlueter Annette J, Lambie Karen, Eaves Connie J, Lansdorp Peter M

Abstract excerpt

Dyskeratosis congenita (DC) is an inherited bone marrow (BM) failure syndrome associated with mutations in telomerase genes and the acquisition of shortened telomeres in blood cells. To investigate the basis of the compromised hematopoiesis seen in DC, we analyzed cells from granulocyte colony-stimulating factor mobilized peripheral blood (mPB) collections from 5 members of a family with autosomal dominant DC...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18310499
DOI: 10.1182/blood-2007-10-120204
PMCID: PMC2343591

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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