Article
Inactivated Sendai virus strain Tianjin, a novel genotype of Sendai virus, inhibits growth of murine colon carcinoma through inducing immune responses and apoptosis.
Journal of translational medicine - 5 Sept 2013
Shi Liying, Chen Jun, Zhong Qiping, Li Mei, Geng Peng, He Jianmin, Han Zhe, Sheng Mingwei, Tang Hua
Abstract excerpt
BACKGROUND: Ultraviolet-inactivated, replication-defective Sendai virus particles (Z strain) have displayed antitumor effect through enhancing the immune responses or inducing apoptosis in a variety of carcinomas. Sendai virus strain Tianjin was isolated from the lungs of marmoset and proved to be a novel genotype of Sendai virus. In this study, we explored the antitumor effect and its mechanism of...
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