Article
RIG-I helicase-independent pathway in sendai virus-activated dendritic cells is critical for preventing lung metastasis of AT6.3 prostate cancer.
Neoplasia (New York, N.Y.) - 1 Nov 2010
Kato Tomonori, Ueda Yasuji, Kinoh Hiroaki, Yoneyama Yasuo, Matsunaga Akinao, Komaru Atsushi, Harada Yui, Suzuki Hiroyoshi, Komiya Akira, Shibata Satoko, Hasegawa Mamoru, Hayashi Hideki, Ichikawa Tomohiko, Yonemitsu Yoshikazu
Abstract excerpt
We recently demonstrated highly efficient antitumor immunity against dermal tumors of B16F10 murine melanoma with the use of dendritic cells (DCs) activated by replication-competent, as well as nontransmissible-type, recombinant Sendai viruses (rSeV), and proposed a new concept, "immunostimulatory virotherapy," for cancer immunotherapy. However, there has been little information on the efficacies of this method:...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.