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Article

Importance of the anti-interferon capacity of Sendai virus C protein for pathogenicity in mice.

Journal of virology - 1 Apr 2007

Kato Atsushi, Kiyotani Katsuhiro, Kubota Toru, Yoshida Tetsuya, Tashiro Masato, Nagai Yoshiyuki

Abstract excerpt

The Sendai virus (SeV) C protein blocks signal transduction of interferon (IFN), thereby counteracting the antiviral actions of IFN. Using HeLa cell lines expressing truncated or mutated SeV C proteins, we found that the C-terminal half has anti-IFN capacity, and that K(151)A, E(153)A, and R(154)A substitutions in the C protein eliminated this capacity. Here, we further created the mutant virus SeV Cm*, in which...

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Identifiers

PMID: 17215288
DOI: 10.1128/JVI.02590-06
PMCID: PMC1866026

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STAT1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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