Article
[Immunogenetic aspects of early rheumatoid arthritis].
Vestnik Rossiiskoi akademii meditsinskikh nauk - 1 Jan 2013
Guseva I A, Demidova N V, Soroka N E, Novikov A A, Luchikhina E L, Aleksandrova E N, Lukina G V, Fedorenko E V, Aronova E S, Samarkina E Iu, Boldyreva M N, Trofimov D Iu, Karateev D E, Nasonov E L
Abstract excerpt
The study is aimed to investigate the distribution of alleles of HLA-DRB1 gene in patients with early rheumatoid arthritis and healthy individuals in Russian population, and evaluate their significance as molecular genetic markers of rheumatoid arthritis predisposition and protection. The association between alleles of HLA-DRB1 genes, antibodies to cyclic citrullinated peptides and IgM rheumatoid factor was also...
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