Article
Three SNPs in chromosome 11q23.3 are independently associated with systemic lupus erythematosus in Asians.
Human molecular genetics - 15 Jan 2014
Zhang Jing, Zhang Yan, Yang Jing, Zhang Lu, Sun Liangdan, Pan Hai-Feng, Hirankarn Nattiya, Ying Dingge, Zeng Shuai, Lee Tsz Leung, Lau Chak Sing, Chan Tak Mao, Leung Alexander Moon Ho, Mok Chi Chiu, Wong Sik Nin, Lee Ka Wing, Ho Marco Hok Kung, Lee Pamela Pui Wah, Chung Brian Hon-Yin, Chong Chun Yin, Wong Raymond Woon Sing, Mok Mo Yin, Wong Wilfred Hing Sang, Tong Kwok Lung, Tse Niko Kei Chiu, Li Xiang-Pei, Avihingsanon Yingyos, Rianthavorn Pornpimol, Deekajorndej Thavatchai, Suphapeetiporn Kanya, Shotelersuk Vorasuk, Ying Shirley King Yee, Fung Samuel Ka Shun, Lai Wai Ming, Garcia-Barceló Maria-Mercè, Cherny Stacey S, Tam Paul Kwong-Hang, Cui Yong, Sham Pak Chung, Yang Sen, Ye Dong Qing, Zhang Xue-Jun, Lau Yu Lung, Yang Wanling
Abstract excerpt
Systemic lupus erythematosus (SLE) has a complex etiology and is affected by both genetic and environmental factors. Although more than 40 loci have shown robust association with SLE, the details of these loci, such as the independent contributors and the genes involved, are still unclear. In this study, we performed meta-analysis of two existing genome-wide association studies (GWASs) on Chinese Han populations...
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