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Article

Engineering and kinetic stabilization of the therapeutic enzyme Anabeana variabilis phenylalanine ammonia lyase.

Applied biochemistry and biotechnology - 1 Dec 2013

Jaliani Hossein Zarei, Farajnia Safar, Mohammadi Seyyed Abolghasem, Barzegar Abolfazl, Talebi Saeed

Abstract excerpt

Anabeana variabilis phenylalanine ammonia lyase has just recently been discovered and introduced in clinical trials of phenylketonuria enzyme replacement therapy for its outstanding kinetic properties. In the present study, kinetic stabilization of this therapeutically important enzyme has been e...

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Identifiers

PMID: 23999738
DOI: 10.1007/s12010-013-0450-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23999738-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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