Article
Oncometabolites: linking altered metabolism with cancer.
The Journal of clinical investigation - 1 Sept 2013
Yang Ming, Soga Tomoyoshi, Pollard Patrick J
Abstract excerpt
The discovery of cancer-associated mutations in genes encoding key metabolic enzymes has provided a direct link between altered metabolism and cancer. Advances in mass spectrometry and nuclear magnetic resonance technologies have facilitated high-resolution metabolite profiling of cells and tumors and identified the accumulation of metabolites associated with specific gene defects. Here we review the potential...
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