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Article

Restoration of the normal Clara cell phenotype after chronic allergic inflammation.

International journal of experimental pathology - 1 Dec 2013

Roth Felix D, Quintar Amado A, Leimgruber Carolina, García Luciana, Uribe Echevarría Elisa M, Torres Alicia I, Maldonado Cristina A

Abstract excerpt

Bronchiolar Clara cells play a critical role in lung homoeostasis. The main goal of this study was to evaluate the effects of chronic allergy on these cells and the efficacy of budesonide (BUD) and montelukast (MK) in restoring their typical phenotypes after ovalbumin-induced chronic allergy in mice. Chronic allergy induced extensive bronchiolar Alcian blue-periodic acid-Schiff (AB/PAS)-positive metaplasia. In...

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Identifiers

PMID: 23998365
DOI: 10.1111/iep.12041
PMCID: PMC3944451

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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