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Article

Gender-specific association of NFKBIA promoter polymorphisms with the risk of sporadic colorectal cancer.

Medical oncology (Northwood, London, England) - 1 Dec 2013

Tan Shing Cheng, Suzairi Mohd Shafi'i Mohd, Aizat Abdul Aziz Ahmad, Aminudin Mustapha Mohd, Nurfatimah Mohd Shahpudin Siti, Bhavaraju Venkata Murali Krishna, Biswal Biswa Mohan, Ankathil Ravindran

Abstract excerpt

The inhibitory protein IκBα, encoded by the NFKBIA gene, plays an important role in regulating the activity of nuclear factor-kappa B, a transcription factor which has been implicated in the initiation and progression of cancers. This study aimed to evaluate the association of NFKBIA -826C>T (rs2233406) and -881A>G (rs3138053) polymorphisms with the risk of sporadic colorectal cancer (CRC) in Malaysian...

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Source

Identifiers

PMID: 23996241
DOI: 10.1007/s12032-013-0693-6

Genes

NFKBIA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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