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Article

Non-canonical translation start sites in the TMEM16A chloride channel.

Biochimica et biophysica acta - 1 Jan 2014

Sondo Elvira, Scudieri Paolo, Tomati Valeria, Caci Emanuela, Mazzone Amelia, Farrugia Gianrico, Ravazzolo Roberto, Galietta Luis J V

Abstract excerpt

TMEM16A is a plasma membrane protein with voltage- and calcium-dependent chloride channel activity. The role of the various TMEM16A domains in expression and function is poorly known. In a previous study, we found that replacing the first ATG of the TMEM16A coding sequence with a nonsense codon (M1X mutation), to force translation from the second ATG localized at position 117, only had minor functional...

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Identifiers

PMID: 23994600
DOI: 10.1016/j.bbamem.2013.08.010
PMCID: PMC3898931

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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