Article
Comparative assessment of the intracellular survival of the Burkholderia pseudomallei bopC mutant.
Journal of microbiology (Seoul, Korea) - 1 Aug 2013
Srinon Varintip, Muangman Sunsiree, Imyaem Nithima, Muangsombut Veerachat, Lazar Adler Natalie R, Galyov Edouard E, Korbsrisate Sunee
Abstract excerpt
Burkholderia pseudomallei, the causative agent of melioidosis, is a Gram-negative saprophytic bacterium capable of surviving within phagocytic cells. To assess the role of BopC (a type III secreted effector protein) in the pathogenesis of B. pseudomallei, a B. pseudomallei bopC mutant was used to infect J774A.1 macrophage-like cells. The bopC mutant showed significantly reduced intracellular survival in infected...
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