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Article

Translational up-regulation of polycystic kidney disease protein PKD2 by endoplasmic reticulum stress.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Dec 2013

Yang Jungwoo, Zheng Wang, Wang Qian, Lara Carlos, Hussein Shaimaa, Chen Xing-Zhen

Abstract excerpt

Autosomal dominant polycystic kidney disease (ADPKD) is caused by mutations in PKD1 or PKD2, and it affects over 10 million people worldwide. It is characterized by cyst formation in the kidney, liver and pancreas. Dosage changes in PKD1/PKD2 are important in ADPKD pathogenesis; therefore, their expression and function has to be strictly regulated. However, how they are regulated remain poorly understood. Recent...

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Source

Identifiers

PMID: 23985800
DOI: 10.1096/fj.13-236075

Genes

PKD2
PKD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Translational up-regulation of polycystic kidney disease protein PKD2 by endoplasmic reticulum stress.PMID 23985800Read ↗

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