Article
The tails of apical scaffolding proteins EBP50 and E3KARP regulate their localization and dynamics.
Molecular biology of the cell - 1 Nov 2013
Garbett Damien, Sauvanet Cécile, Viswanatha Raghuvir, Bretscher Anthony
Abstract excerpt
The closely related apical scaffolding proteins ERM-binding phosphoprotein of 50 kDa (EBP50) and NHE3 kinase A regulatory protein (E3KARP) both consist of two postsynaptic density 95/disks large/zona occludens-1 (PDZ) domains and a tail ending in an ezrin-binding domain. Scaffolding proteins are thought to provide stable linkages between components of multiprotein complexes, yet in several types of epithelial...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
