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Article

Proximity interactome of lymphatic VE-cadherin reveals mechanisms of junctional remodeling and reelin secretion

4 Sept 2024

Abstract excerpt

The adhesion receptor vascular endothelial (VE)-cadherin transduces an array of signals that modulate crucial lymphatic cell behaviors including permeability and cytoskeletal remodeling. Consequently, VE-cadherin must interact with a multitude of intracellular proteins to exert these functions. Yet, the full protein interactome of VE-cadherin in endothelial cells remains a mystery. Here, we use proximity...

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Identifiers

PMID: 39232006
DOI: 10.1038/s41467-024-51918-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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Semantic proximity does not establish scientific evidence.

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