Effect of mutations in domain 2 on the structural organization of oocyte 5 S rRNA from Xenopus laevis.

doi:10.1016/S0022-2836(05)80099-3

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Article

Effect of mutations in domain 2 on the structural organization of oocyte 5 S rRNA from Xenopus laevis.

Journal of molecular biology - 5 Sept 1990

Brunel C, Romby P, Westhof E, Romaniuk P J, Ehresmann B, Ehresmann C

Abstract excerpt

In order to test and refine the molecular model of Xenopus laevis 5 S rRNA proposed in a previous work, we have synthesized, by site-directed mutagenesis and in vitro transcription, four mutants in the internal loop B and in the hairpin loop C of domain 2. The conformations of these mutant 5 S rR...

Topics

Animals
Base Composition
Base Sequence
Female
Models, Molecular
Molecular Sequence Data
Mutation
Nucleic Acid Conformation
Oocytes
RNA, Ribosomal
RNA, Ribosomal, 5S
Xenopus laevis

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