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Article

An evolutionary intra-molecular shift in the preferred U3 snoRNA binding site on pre-ribosomal RNA.

Nucleic acids research - 1 Jan 2005

Borovjagin Anton V, Gerbi Susan A

Abstract excerpt

Correct docking of U3 small nucleolar RNA (snoRNA) on pre-ribosomal RNA (pre-rRNA) is essential for rRNA processing to produce 18S rRNA. In this report, we have used Xenopus oocytes to characterize the structural requirements of the U3 snoRNA 3'-hinge interaction with region E1 of the external transcribed spacer (ETS) of pre-rRNA. This interaction is crucial for docking to initiate rRNA processing. 18S rRNA...

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Identifiers

PMID: 16147982
DOI: 10.1093/nar/gki815
PMCID: PMC1199564

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Source receipt: pubmed, retrieved 7 Sept 2026.

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An evolutionary intra-molecular shift in the preferred U3 snoRNA binding site on pre-ribosomal RNA.PMID 16147982Read ↗

Xenopus U3 snoRNA docks on pre-rRNA through a novel base-pairing interaction.Semantic proximity Read ↗

The spacing between functional Cis-elements of U3 snoRNA is critical for rRNA processing.Semantic proximity Read ↗

Trypanosoma brucei 5'ETS A'-cleavage is directed by 3'-adjacent sequences, but not two U3 snoRNA-binding elements, which are all required for subsequent pre-small subunit rRNA processing events.Semantic proximity Read ↗

A second base pair interaction between U3 small nucleolar RNA and the 5'-ETS region is required for early cleavage of the yeast pre-ribosomal RNA.Semantic proximity Read ↗

The U14 snoRNA is required for 2'-O-methylation of the pre-18S rRNA in Xenopus oocytes.Semantic proximity Read ↗

An unexpected, conserved element of the U3 snoRNA is required for Mpp10p association.Semantic proximity Read ↗

Synergistic defects in pre-rRNA processing from mutations in the U3-specific protein Rrp9 and U3 snoRNA.Semantic proximity Read ↗

Functional base-pairing interaction between highly conserved elements of U3 small nucleolar RNA and the small ribosomal subunit RNA.Semantic proximity Read ↗

Ribosomal protein L3 functions as a 'rocker switch' to aid in coordinating of large subunit-associated functions in eukaryotes and Archaea.Semantic proximity Read ↗

Essential structural features in the Schizosaccharomyces pombe pre-rRNA 5' external transcribed spacer.Semantic proximity Read ↗

Base pairing between U3 small nucleolar RNA and the 5' end of 18S rRNA is required for pre-rRNA processing.Semantic proximity Read ↗

Ribosomal 18S rRNA base pairs with mRNA during eukaryotic translation initiation.Semantic proximity Read ↗

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