Article
A mutant form of the ribosomal protein L1 reveals conformational flexibility.
FEBS letters - 7 Jul 1997
Unge J, Al-Karadaghi S, Liljas A, Jonsson B H, Eliseikina I, Ossina N, Nevskaya N, Fomenkova N, Garber M, Nikonov S
Abstract excerpt
The crystal structure of the mutant S179C of the ribosomal protein L1 from Thermus thermophilus has been determined at 1.9 A resolution. The mutant molecule displays a small but significant opening of the cavity between the two domains. The domain movement seems to be facilitated by the flexibility of at least two conserved glycines. These glycines may be necessary for the larger conformational change needed for...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.