Article
Immunoinformatic docking approach for the analysis of KIR3DL1/HLA-B interaction.
BioMed research international - 1 Jan 2013
Grifoni Alba, Montesano Carla, Patronov Atanas, Colizzi Vittorio, Amicosante Massimo
Abstract excerpt
KIR3DL1 is among the most interesting receptors studied, within the killer immunoglobulin receptor (KIR) family. Human leukocyte antigen (HLA) class I Bw4 epitope inhibits strongly Natural Killer (NK) cell's activity through interaction with KIR3DL1 receptor, while Bw6 generally does not. This interaction has been indicated to play an important role in the immune control of different viral infectious diseases....
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