Article
QSAR study on MHC class I a alleles based on the novel parameters of amino acids.
Protein and peptide letters - 1 Sept 2011
Wang Juan, Wang Xiao-Yu, Shu Mao, Wang Yuan-Qiang, Lin Yong, Wang Li, Cheng Xiao-Ming, Lin Zhi-Hua
Abstract excerpt
MHC-epitope binding plays a key role in the cellular immune response. Accurate prediction of MHC-epitope binding affinity can greatly expedite epitope screening by reducing costs and experimental effort. In this paper, 13 T descriptors, which derived from 544 physicochemical properties of the natural amino acids, were used to characterize 4 MHC class I alleles epitope peptide sequences, the optimal QSAR models...
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