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Article

Genetic and epigenetic characteristics of patients with colorectal cancer from Uruguay.

Pathology, research and practice - 1 Jan 2023

Vital Marcelo, Carusso Florencia, Vergara Carolina, Neffa Florencia, Della Valle Adriana, Esperón Patricia

Abstract excerpt

Colorectal cancer (CRC), the 3rd most frequent cancer worldwide, affects both men and women. This pathology arises from the progressive accumulation of genetic and epigenetic alterations. In this study, KRAS, NRAS, PIK3CA, and BRAF gene mutations, mismatch repair (MMR) genes methylation profile, microsatellite instability (MSI) and CpG Island Methylator Phenotype (CIMP) status were assessed. The associations of...

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Identifiers

PMID: 36495761
DOI: 10.1016/j.prp.2022.154264

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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