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A novel serogenetic approach determines the community prevalence of celiac disease and informs improved diagnostic pathways

28 Aug 2013

Abstract excerpt

BACKGROUND: Changing perspectives on the natural history of celiac disease (CD), new serology and genetic tests, and amended histological criteria for diagnosis cast doubt on past prevalence estimates for CD. We set out to establish a more accurate prevalence estimate for CD using a novel serogenetic approach. METHODS: The human leukocyte antigen (HLA)-DQ genotype was determined in 356 patients with...

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PMID: 23981538
DOI: 10.1186/1741-7015-11-188

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