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Article

Acidic residues comprise part of the myosin light chain-binding site on skeletal muscle myosin light chain kinase.

The Journal of biological chemistry - 25 Sept 1990

Herring B P, Fitzsimons D P, Stull J T, Gallagher P J

Abstract excerpt

Myosin light chain kinase is a Ca2+/calmodulin-dependent protein kinase which exhibits a very high degree of protein substrate specificity. The regulatory light chain of myosin is the only known physiological substrate of the enzyme. Based upon epitope mapping of monoclonal antibodies which inhibit kinase activity competitively with respect to the light chain substrate, residues 235-319 of the rabbit skeletal...

Topics

Amino Acid Sequence
Animals
Base Sequence
Binding Sites
Kinetics
Molecular Sequence Data
Muscles
Mutation
Myosin Subfragments
Myosin-Light-Chain Kinase
Oligonucleotide Probes

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Identifiers

PMID: 2398065
PMCID: PMC2836771

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2398065-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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