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Article

Intrasteric regulation of myosin light chain kinase.

The Journal of biological chemistry - 14 Jul 1995

Krueger J K, Padre R C, Stull J T

Abstract excerpt

Ca2+/calmodulin activates myosin light chain kinase by reversal of an autoinhibited state. The effects of substitution mutations on calmodulin activation properties implicate 4 of the 8 basic residues between the catalytic core and the calmodulin-binding domain in maintaining autoinhibition. These residues are further amino-terminal to the basic residues comprising the previously proposed pseudosubstrate sequence...

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Identifiers

PMID: 7622500
DOI: 10.1074/jbc.270.28.16848

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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