Article
Homodimerization of the Wnt receptor DERAILED recruits the Src family kinase SRC64B.
Molecular and cellular biology - 1 Oct 2013
Petrova Iveta M, Lahaye Liza L, Martiáñez Tania, de Jong Anja W M, Malessy Martijn J, Verhaagen Joost, Noordermeer Jasprina N, Fradkin Lee G
Abstract excerpt
Ryk pseudokinase receptors act as important transducers of Wnt signals, particularly in the nervous system. Little is known, however, of their interactions at the cell surface. Here, we show that a Drosophila Ryk family member, DERAILED (DRL), forms cell surface homodimers and can also heterodime...
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