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Article

Considerations for subgroups and phenocopies in complex disease genetics.

PloS one - 1 Jan 2013

Ramanujam Ryan, Ramanujam S, Hillert Jan

Abstract excerpt

The number of identified genetic variants associated to complex disease cannot fully explain heritability. This may be partially due to more complicated patterns of predisposition than previously suspected. Diseases such as multiple sclerosis (MS) may consist of multiple disease causing mechanisms, each comprised of several elements. We describe how the effect of subgroups can be calculated using the standard...

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Identifiers

PMID: 23977088
DOI: 10.1371/journal.pone.0071614
PMCID: PMC3748062

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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