Article
[Morphological analysis of the hippocampal region associated with an innate behaviour task in the transgenic mouse model (3xTg-AD) for Alzheimer disease].
Neurologia (Barcelona, Spain) - 1 Oct 2013
Orta-Salazar E, Feria-Velasco A, Medina-Aguirre G I, Díaz-Cintra S
Abstract excerpt
INTRODUCTION: Different animal models for Alzheimer disease (AD) have been designed to support the hypothesis that the neurodegeneration (loss of neurons and synapses with reactive gliosis) associated with Aβ and tau deposition in these models is similar to that in the human brain. These alterations produce functional changes beginning with decreased ability to carry out daily and social life activities, memory...
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