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Article

Aldehyde dehydrogenase activity selects for the holoclone phenotype in prostate cancer cells.

Biochemical and biophysical research communications - 4 Nov 2011

Doherty R E, Haywood-Small S L, Sisley K, Cross N A

Abstract excerpt

Aldehyde dehydrogenase 1 (ALDH) activity is considered to be a marker of cancer stem cells (CSCs) in many tumour models, since these cells are more proliferative and tumourigenic than ALDH(Lo) cells in experimental models. However it is unclear whether all CSC-like cells are within the ALDH(Hi) population, or whether all ALDH(Hi) cells are highly proliferative and tumourigenic. The ability to establish a stem...

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Identifiers

PMID: 22005464
DOI: 10.1016/j.bbrc.2011.10.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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