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Article

miR‑221 inhibits autophagy and targets TP53INP1 in colorectal cancer cells

16 Nov 2017

Abstract excerpt

Colorectal cancer (CRC) is the third most common cancer and the fourth leading cause of cancer-associated mortalities worldwide. MicroRNAs (miRNAs/miRs) serve important roles in tumor development, progression and metastasis. miR-221 has been reported to modulate proliferation, apoptosis, cell cycle distribution and cell migration in a variety of cancers. However, the function of miR-221 in the autophagy of cancer...

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PMID: 29434757
DOI: 10.3892/etm.2017.5522

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