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Article

Genetic alterations in thyroid tumors from patients irradiated in childhood for tinea capitis treatment.

European journal of endocrinology - 1 Nov 2013

Boaventura Paula, Pereira Dina, Celestino Ricardo, Mendes Adélia, Nakasawa Tadao, Teixeira-Gomes José, Sobrinho-Simões Manuel, Soares Paula

Abstract excerpt

OBJECTIVE: Exposure to ionizing radiation at young age is the strongest risk factor for the occurrence of papillary thyroid carcinoma (PTC). RET/PTC rearrangements are the most frequent genetic alterations associated with radiation-induced PTC, whereas BRAF and RAS mutations and PAX8-PPARG rearrangement have been associated with sporadic PTC. We decided to search for such genetic alterations in PTCs of patients...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23966419
DOI: 10.1530/EJE-13-0543

Genes

BRAF
RET
PAX8
PPARG
NRAS

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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