Article
Frequent BRAF V600E and Absence of TERT Promoter Mutations Characterize Sporadic Pediatric Papillary Thyroid Carcinomas in Japan.
Endocrine pathology - 1 Jun 2017
Oishi Naoki, Kondo Tetsuo, Nakazawa Tadao, Mochizuki Kunio, Inoue Tomohiro, Kasai Kazunari, Tahara Ippei, Yabuta Tomonori, Hirokawa Mitsuyoshi, Miyauchi Akira, Katoh Ryohei
Abstract excerpt
Pediatric papillary thyroid carcinoma (PTC) has unique features but requires further genetic investigation. Moreover, there has been increasing concern about the risk for pediatric PTC in Japan after the Fukushima accident. This study aims to evaluate the frequencies of BRAF and TERT promoter mutations and to examine their significance in non-radiation-associated pediatric PTCs in Japan. We enrolled 81 pediatric...
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