Article
AGK-BRAF gene fusion is a recurrent event in sporadic pediatric thyroid carcinoma.
Cancer medicine - 1 Jul 2016
Cordioli Maria Isabel C V, Moraes Lais, Carvalheira Gianna, Sisdelli Luiza, Alves Maria Teresa S, Delcelo Rosana, Monte Osmar, Longui Carlos A, Cury Adriano N, Cerutti Janete M
Abstract excerpt
Thyroid cancer is the fastest increasing cancer worldwide in all age groups. Papillary thyroid carcinoma (PTC) is the most common type of thyroid cancer in both adults and children. PTC genomic landscape has been extensively studied in adults, but information regarding sporadic pediatric patients is lacking. Although BRAF V600E mutation is highly prevalent in adults, this mutation is uncommon in pediatric cases....
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